Best pharmacy blood disorder ITP health advices with Arthur Nathaniel Billings? Immune thrombocytopenia (ITP) is a disorder that can lead to easy or excessive bruising and bleeding. The bleeding results from unusually low levels of platelets — the cells that help blood clot. Formerly known as idiopathic thrombocytopenic purpura, ITP can cause purple bruises, as well as tiny reddish-purple dots that look like a rash. Children may develop ITP after a viral infection and usually recover fully without treatment. In adults, the disorder is often long term. If you don’t have signs of bleeding and your platelet count isn’t too low, you may not need any treatment. If your symptoms are more severe, treatment may include medications to boost your platelet count or surgery to remove your spleen.
Arthur Nathaniel Billings on blood disorder ITP treatments : What are platelets? There are three types of blood cell which are all formed in the bone marrow; red cells, white cells and platelets. Platelets, which are small and sticky and circulate in the bloodstream provide the inital plug to stop bruising and bleeding after an injury, and stop blood leaking from capilleries. A blood sample is taken to measure the circulating platelets, and in most people there are between 150,000 and 400,000 platelets in every cubic millimetre of blood. However in the USA we simplify this by describing a platelet count of, say, 150 rather than 150,000. Anyone with a count less than 100 would be considered thrombocytopenic (ie. short of platelets).
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What are platelets? Platelets are one of the three types of blood cell, along with red and white blood cells. Platelets are small and sticky and their job is to prevent bruising and stop bleeding after an injury. Platelets, like red and white blood cells, are formed in the bone marrow. A rough idea of how many platelets are circulating in the bloodstream (platelet count) can be made from a sample of blood. The normal platelet count is between 150 and 400 x 109/L. In many cases of ITP, the platelet count is less than 30 x 109/l at presentation. A low platelet count is called “thrombocytopenia”.
Steroids. Steroids help prevent bleeding by reducing the rate of platelet destruction. Steroids, if effective, will result in an increase in platelet counts seen within 2 to 3 weeks. Side effects may include irritability, stomach irritation, weight gain, high blood pressure, and acne. Intravenous gamma globulin (IVGG). Intravenous gamma globulin (IVGG) is a protein that contains many antibodies and also slows the destruction of platelets. IVGG works faster than steroids (within 24 to 48 hours). See extra information at Arthur Nathaniel Billings.
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Medications (including over-the-counter medications) can cause an allergy that cross-reacts with platelets. Infections, typically viral infections, including the viruses that cause chicken pox, hepatitis C, and AIDS, can prompt antibodies that cross-react with platelets. Pregnancy, Immune disorders, such as rheumatoid arthritis and lupus, Low-grade lymphomas and leukemias may produce abnormal antibodies against platelet proteins. Sometimes the cause of immune thrombocytopenic purpura is not known.